P&F Studies

2020
Pilot Awardee	Center	Pilot Study
Uma Sankar PhD	Indiana University	Harnessing bone-mediated regulation of diabetes
Jarrad Scarlett MD PhD	University of Washington	Hypothalamic Mechanisms Mediating Sustained Glucose-Lowering by FGF1 Action in the Brain
Mia Smith DVM PhD	University of Colorado Denver	Decoding the B cell endotype in early onset T1D
Jason Spaeth PhD	Indiana University	Dynamic regulations of Pdx1 activity and beta cell function and identity through the Snd1 coregulator
Diana Stanescu MD	University of Pennsylvania	The role of SLC38A5 in pancreatic α cell development
Christoph Thaiss PhD	University of Pennsylvania	Microbiome-clock interactions in metabolic disease
Linus Tzu-Yen Tsai MD PhD	Joslin Diabetes Center	The role of interferon regulatory factors in tanycytes during HFD-induced inflammation, obesity and glucose dysregulation
Xiaoxiao Wan MD PhD	Washington University in St Louis	Explore the Immunosuppressive Effects of Monoclonal Insulin Autoantibodies in Type 1 Diabetes
Luke Wander MD MS	University of Washington	Identifying miRNA-Mediated Mechanisms Driving the Protective Effects of Metformin on Beta-Cell Function
Jessica Williams PhD	University of Alabama at Birmingham	Clinician Implicit Bias and Perceived Barriers to Medication Intensification: A Pilot & Feasibility Study
Jessica Wilson MD MS	University of Pennsylvania	Metabolic Phenotype and Type 2 Diabetes Polygenic Risk Score
Clyde Wright MD	University of Colorado Denver	Pathogenic Role of IκBβ/NFκB signaling in ER Stress Induced β-cell Injury and Death
Min Xie MD PhD	University of Alabama at Birmingham	HDAC Upregulation by Chronic Beta-Hydroybutyrate Exposure Exacerbates Ischemia/Reperfusion Injury During Diabetes Mellitus
Richard Zare, PhD	Stanford University	Development and Validation of an Enabling Methodology for Measuring Islet-Specific Drug Delivery in vivo