P&F Studies

2024
Pilot Awardee	Center	Pilot Study
Xiaojuan Chen MD PhD	Columbia University	The in vivo function and dysfunction of human α-cells derived from stem cells or in pseudo T1D-islets
Ke Cheng PhD	Columbia University	Novel microRNA therapy for Type 2 diabetes
Rebecca A Haeusler PhD	Columbia University	Regulation of Akt conformation and function
Charles LeDuc PhD	Columbia University	Assessing the effects of placental insulin signaling on the offspring
Vidhu Thaker MD	Columbia University	Assessing the effects of placental insulin signaling on the offspring

2023
Pilot Awardee	Center	Pilot Study
Nancy Carrasco MD	Vanderbilt University	Uncovering the mechanisms of acute overnutrition-induced thyroid dysfunction
Juan Alvarez PhD	University of Pennsylvania	Linking functional maturity to the human islet inflammatory response via integrated bioelectronics & spatial transcriptomic
Joseph Baur PhD	University of Pennsylvania	Integration of glucose telemetry with indirect calorimetry
Ambre Bertholet PhD	UCSD-UCLA	A thermogenic alternative to UCP1-dependent H+ current in brown adipose tissue
Maigen Bethea PhD	University of Colorado Denver	The Role of Gastrointestinal GLP-1R Neurons in Mediating the Glucose-Lowering and Weight Loss Effects of Oral Exendin-4
Michael Betts PhD	University of Pennsylvania	Islet-specific memory T cell responses upon autologous islet exposure
Romina Bevacqua PhD	Albert Einstein College of Medicine	Innovative Genetic Technologies For Identifying Novel Regulatory Mechanisms Controlling Human b-Cell Maturation and Function
Vijay Bjoh MD PhD	University of Pennsylvania	Evaluation of B-cell Targeted CAR T Cells to Induce Durable Beta Islet Cell Tolerance in Type-1 Diabetes
Kate Townsend Creasy PhD	University of Pennsylvania	Evaluating a ketogenic diet for the treatment of genetic disorders of glycogen metabolism