Diabetes Research Centers (P30 Clinical Trial Optional)
This Funding Opportunity Announcement (FOA) invites applications for Diabetes Research Centers that are designed to support and enhance the national research effort in diabetes, its complications, and related endocrine and metabolic diseases. Diabetes Research Centers support two primary research-related activities: Research Core services and a Pilot and Feasibility (P and F) program.

DIABETES RESEARCH CENTERS

Jeffrey S Elmendorf Jeffrey S Elmendorf PhD Indiana University Indiana University
Dr. Elmendorf's research over the past 20 years has been focused on dissecting mechanisms regulating skeletal muscle and adipose tissue glucose transport and defining their alterations in insulin resistance. The Center for Diabetes and Metabolic Diseases (CDMD) at IU School of Medicine is a world-renowned center focused on centralizing and fostering research along five fundamental themes to strengthen the diabetes research base throughout Indiana.
Michael Rickels MD MS University of Pennsylvania University of Pennsylvania
Dr. Rickels conducts patient-oriented diabetes research that aims at understanding the pathogenesis of different types of diabetes and the in vivo mechanisms of new diabetes treatments. The Penn Diabetes Research Center participates in the nationwide inter-disciplinary program established over forty years ago by the NIDDK to foster research and training in the areas of diabetes and related endocrine and metabolic disorders.
Joel Habener Joel Habener MD Boston Area Boston Area
Dr. Habener is Professor of Medicine at Harvard Medical School and Associate Physician and Chief of the Laboratory of Molecular Endocrinology at Massachusetts General Hospital, Boston. The Boston Area Diabetes Endocrinology Research Center is a consortium of laboratory-based and clinical investigators whose efforts are directed toward addressing many of the major research questions bearing on the etiology, pathogenesis, treatment and cure of type 1 and type 2 diabetes.
W Timothy Garvey W Timothy Garvey MD University of Alabama at Birmingham University of Alabama at Birmingham
The Garvey laboratory is interested in the molecular, metabolic, and genetic basis of type 2 diabetes mellitus, insulin resistance, and obesity. The Diabetes Research and Training Center (DRC) focuses on developing new methods to treat, prevent, and ultimately cure diabetes and its complications.
Mitchell A Lazar MD PhD University of Pennsylvania University of Pennsylvania
The Lazar laboratory is studying the transcriptional regulation of metabolism. We are particularly focused on the role played by nuclear receptors. The Penn Diabetes Research Center participates in the nationwide inter-disciplinary program established over forty years ago by the NIDDK to foster research and training in the areas of diabetes and related endocrine and metabolic disorders.
Alvin C Powers MD Vanderbilt University Vanderbilt University
The purpose of our research is to understand how glucose stimulates insulin secretion by pancreatic islet cells and to characterize and reverse abnormalities in this process that are present in diabetes. The Vanderbilt Diabetes Research and Training Center (DRTC), is a NIH-sponsored Diabetes Center that facilitates the discovery, application, and translation of scientific knowledge to improve the lives of people with diabetes.
Qizhi Tang Qizhi Tang PhD UCSF UCSF
The Tang lab focuses on translating knowledge on mechanisms of immune tolerance into novel therapeutics for treating autoimmune diabetes and preventing transplant rejection. The University of California San Francisco Diabetes Research Center (UCSF DRC) is one of only 16 research centers established by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to accelerate basic and clinical research into diabetes.
Fredric Kraemer MD Stanford University Stanford University
Dr. Fredric Kraemer is the Chief of the Division of Endocrinology, Gerontology and Metabolism. He is a board certified endocrinologist for over 35 years who specializes in the treatment diabetes mellitus, particularly type 1 diabetes, and the treatment of lipid disorders, such as elevated cholesterol or triglycerides. The mission of the Stanford Diabetes Research Center is to support basic and clinical research to discover, apply and translate science about diabetes and it complications, to improve health and wellness.
Seung K Kim Seung K Kim MD PhD Stanford University Stanford University
Seung K. Kim is Professor in the Department of Developmental Biology and, by courtesy, in the Department of Medicine (Oncology Division) at Stanford University School of Medicine, where he has been a faculty member since 1998. The mission of the Stanford Diabetes Research Center is to support basic and clinical research to discover, apply and translate science about diabetes and it complications, to improve health and wellness.
Rexford S Ahima Rexford S Ahima MD PhD Johns Hopkins University - University of Maryland Johns Hopkins University - University of Maryland
Dr. Ahima is the Director of the Division of Endocrinology, Diabetes and Metabolism, Bloomberg Distinguished Professor of Diabetes in the Schools of Medicine, Public Health and Nursing, and the leader of the Johns Hopkins Diabetes Initiative. The Johns Hopkins University - University of Maryland Diabetes Research Center fosters collaborative, multidisciplinary diabetes and endocrinology research, and translates that research into programs that advance the diagnosis and management of diabetes mellitus by health care professionals.
Michael Sturek Michael Sturek PhD Indiana University Indiana University
The general aim of our research program is to understand cellular and molecular Ca signaling mechanisms for in vivo cardiovascular phenomena. The Center for Diabetes and Metabolic Diseases (CDMD) at IU School of Medicine is a world-renowned center focused on centralizing and fostering research along five fundamental themes to strengthen the diabetes research base throughout Indiana.
Owen McGuinness PhD Vanderbilt University Vanderbilt University

Our studies focus on the regulation of hepatic and muscle glucose disposal during infection and inflammation. We examine its interaction with obesity and nutritional support. Our approach is to assess metabolism using a combination of tracer and arterio-venous difference techniques in conscious chronically catheterized conscious dogs and mice.

The Vanderbilt Diabetes Research and Training Center (DRTC), is a NIH-sponsored Diabetes Center that facilitates the discovery, application, and translation of scientific knowledge to improve the lives of people with diabetes.
Louis Philipson Louis Philipson MD PhD University of Alabama at Birmingham University of Alabama at Birmingham
Louis Philipson, MD, PhD, is an endocrinologist and a leading world authority on diabetes mellitus. His clinical interests include type 1 diabetes, complicated type 2 diabetes, monogenic diabetes and hypoglycemia. The Diabetes Research and Training Center (DRC) focuses on developing new methods to treat, prevent, and ultimately cure diabetes and its complications.
Pamela L Mellon PhD UCSD-UCLA UCSD-UCLA
We are interested in how the brain controls reproduction through the neuroendocrine system with emphases on development, hormone signaling, gene expression, circadian rhythm, and mouse models of human disease. The overall mission of the UCSD-UCLA DRC is to foster research in theprevention and treatment of diabetes and its complications, and to improve the lives of patients suffering from this devastating disease.
Mark O Goodarzi MD PhD UCSD-UCLA UCSD-UCLA

The laboratory of Mark O. Goodarzi, MD, PhD, seeks to identify genetic factors underlying conditions related to insulin resistance and the metabolic syndrome, using a population genetic approach.

The overall mission of the UCSD-UCLA DRC is to foster research in theprevention and treatment of diabetes and its complications, and to improve the lives of patients suffering from this devastating disease.
Fumihiko Urano Fumihiko Urano MD PhD Washington University in St Louis Washington University in St Louis
Dr. Urano’s current main focus is to find a cure for juvenile diabetes and genetic forms of diabetes including Type 1 diabetes and Wolfram syndrome using stem cell-based therapeutics and gene-based diagnostics. TThe mission of the Washington University School of Medicine (WUSM) Diabetes Research Center (DRC) is to support and enhance research in diabetes and related metabolic diseases.

Diabetes Centers Overview

Diabetes Centers

NIDDK Diabetes Centers

The NIDDK-supported Diabetes Research Centers (DRCs) are part of an integrated program of diabetes and related endocrinology and metabolism research. NIDDK’s Diabetes Centers program supports extramural research institutions that have established an existing base of high-quality, diabetes-related research. Centers provide increased, cost effective collaboration among multidisciplinary groups of investigators at institutions with an established, comprehensive research base in diabetes and related areas of endocrinology and metabolism. DRCs are intended to improve the quality and multidisciplinary nature of research on diabetes by providing shared access to specialized technical resources and expertise. DRCs are intended to facilitate progress in research with the goal of developing new methods to treat, prevent and ultimately cure diabetes mellitus and its complications.

In the Spotlight

Pilot & Feasibility Study
Center Publication
Boston Area Boston Area 
Genome-wide RNAi Screen for Fat Regulatory Genes in C. elegans Identifies a Proteostasis-AMPK Axis Critical for Starvation Survival., Webster, Christopher M., Pino Elizabeth C., Carr Christopher E., Wu Lianfeng, Zhou Ben, Cedillo Lucydalila, Kacergis Michael C., Curran Sean P., and Soukas Alexander A. , Cell Rep, 2017 07 18, Volume 20, Issue 3, p.627-640, (2017)
NIDDK Center
The Cystic Fibrosis Research and Translation Centers are part of an integrated program of research support designed to enhance multidisciplinary research in pathogenesis and treatment of cystic fibrosis.
Diabetes Resource
The centers that make up the ACE program conduct clinical trials and basic research on new immune-based therapies for autoimmune diseases.