Diabetes Research Centers (P30 Clinical Trial Optional)
This Funding Opportunity Announcement (FOA) invites applications for Diabetes Research Centers that are designed to support and enhance the national research effort in diabetes, its complications, and related endocrine and metabolic diseases. Diabetes Research Centers support two primary research-related activities: Research Core services and a Pilot and Feasibility (P and F) program.

DIABETES RESEARCH CENTERS

Barbara Gower Barbara Gower PhD University of Alabama at Birmingham University of Alabama at Birmingham
Dr. Gower research interests are related to obesity and energy metabolism, with an emphasis on insulin secretion/action and the role of the endocrine system The Diabetes Research and Training Center (DRC) focuses on developing new methods to treat, prevent, and ultimately cure diabetes and its complications.
Julian P Whitelegge Julian P Whitelegge PhD UCSD-UCLA UCSD-UCLA
Julian Whitelegge received his Ph.D. from Imperial College of Science and Technology, University of London in 1989 and became heavily involved in mass spectrometry research in the mid nineties. The overall mission of the UCSD-UCLA DRC is to foster research in theprevention and treatment of diabetes and its complications, and to improve the lives of patients suffering from this devastating disease.
Irwin J Kurland MD PhD Albert Einstein College of Medicine Albert Einstein College of Medicine
My laboratory has developed stable isotope based flux phenotyping methodology based on gas chromatography/mass spectrometry (GC/MS) to follow the “history” of glucose and other labeled substrates as they are exchanged between different organs or within the same organ. The Einstein-Mount Sinai Diabetes Research Center (ES-DRC) comprises a vibrant, extensive, diverse, well-funded and highly productive program that provides the foundation for high-quality and cutting-edge research in diabetes and related studies in obesity, metabolism and endocrinology.
Amy Wagers Amy Wagers PhD Joslin Diabetes Center Joslin Diabetes Center
Work in Amy Wagers' laboratory focuses on defining how changes in stem cell activity impact tissue regeneration throughout life and identifying the physiological and pathological signals that modulate stem cell function in an age-dependent manner. Since its inception in 1898, the primary mission of the Joslin Diabetes Center has been to care for people with diabetes, and conduct research to provide new knowledge about diabetes and its complications that will lead to new treatments, prevention and/or cure of these disorders.
Kieren Mather Kieren Mather MD Indiana University Indiana University
Dr Mather’s research focuses on metabolic dysfunction in diabetes and pre diabetic obesity in humans, and how this metabolic dysfunction influences cardiac and vascular function. The mission of the new, integrated Indiana Diabetes Research Center (IDRC) is to foster knowledge, support training, and promote basic and translational research in diabetes and related metabolic disorders, and their complications.
Jeffrey E Pessin PhD Albert Einstein College of Medicine Albert Einstein College of Medicine
The Pessin laboratory is analyzing insulin signaling at the molecular level, the regulation of glucose uptake and metabolism at the cellular, molecular level and the integrative systems of metabolism in normal and pathophysiologic states in genetic rodent models. The Einstein-Mount Sinai Diabetes Research Center (ES-DRC) comprises a vibrant, extensive, diverse, well-funded and highly productive program that provides the foundation for high-quality and cutting-edge research in diabetes and related studies in obesity, metabolism and endocrinology.
Jean E Schaffer Jean E Schaffer MD Washington University in St Louis Washington University in St Louis
The goals of our work are to characterize the fundamental cellular mechanisms of metabolic stress from substrate excess, and to understand how this process contributes to diabetes complications. TThe mission of the Washington University School of Medicine (WUSM) Diabetes Research Center (DRC) is to support and enhance research in diabetes and related metabolic diseases.
Seung K Kim Seung K Kim MD PhD Stanford University Stanford University
Seung K. Kim is Professor in the Department of Developmental Biology and, by courtesy, in the Department of Medicine (Oncology Division) at Stanford University School of Medicine, where he has been a faculty member since 1998. The mission of the Stanford Diabetes Research Center is to support basic and clinical research to discover, apply and translate science about diabetes and it complications, to improve health and wellness.
F Xavier Pi-Sunyer MD MPH Columbia University Columbia University
Dr. Pi-Sunyer's research is directed at understanding the metabolic antecedents of obesity. Studies are in progress exploring the relationship of thermogenic responses (at rest, and to food or to exercise) to the development and maintenance of obesity. The Columbia University Diabetes and Endocrinology Research Center provides research support for investigators pursuing research on diabetes and metabolic disorders.
Raghavendra G Mirmira MD PhD Indiana University Indiana University
Dr. Mirmira’s research program over the past 10 years has centered upon the biology of islets as it relates to islet development/growth, maintenance, and survival. The mission of the new, integrated Indiana Diabetes Research Center (IDRC) is to foster knowledge, support training, and promote basic and translational research in diabetes and related metabolic disorders, and their complications.
Roland W Stein Roland W Stein PhD Vanderbilt University Vanderbilt University
Until recently, little detailed information was known about the factors controlling pancreas development and islet beta cell function. However, our understanding has increased greatly with the identification and molecular characterization of the islet-enriched MafA, MafB, and PDX-1 transcription factors. The Vanderbilt Diabetes Research and Training Center (DRTC), is a NIH-sponsored Diabetes Center that facilitates the discovery, application, and translation of scientific knowledge to improve the lives of people with diabetes.
David Maahs MD PhD Stanford University Stanford University
Dr. Maahs is Professor of Pediatrics and Division Chief of Pediatric Endocrinology at Stanford University and the Lucile Packard Children’s Hospital. His research focuses on improving care and preventing complications in people with type 1 diabetes (T1D). The mission of the Stanford Diabetes Research Center is to support basic and clinical research to discover, apply and translate science about diabetes and it complications, to improve health and wellness.
Christopher K Glass Christopher K Glass MD PhD UCSD-UCLA UCSD-UCLA
Christopher K. Glass is Professor of Cellular and Molecular Medicine and Professor of Medicine at the University of California, San Diego School of Medicine. The overall mission of the UCSD-UCLA DRC is to foster research in theprevention and treatment of diabetes and its complications, and to improve the lives of patients suffering from this devastating disease.
Raimund I Herzog Raimund I Herzog MD MHS Yale University Yale University
Dr. Herzog’s laboratory is focused on characterizing and preventing its central nervous complications. He uses state-of-the-art technologies to define the impact of diabetes and intensive insulin treatment on brain metabolism and cognition. The Yale Diabetes Research Center (DRC) was established in the spring of 1993 with the goal of promoting research in diabetes and related metabolic and endocrine disorders at the university.
Michael German Michael German MD UCSF UCSF
Dr. German is the Associate Director and Clinical Director of the UCSF Diabetes Center, Director of the the Hillblom Islet Genesis Network and the UCSF NIH Diabetes Research Center (DRC). The UC San Francisco (UCSF) Diabetes Research Center (DRC) is one of only 16 research centers established by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to accelerate basic and clinical research into diabetes.
Mitchell A Lazar MD PhD University of Pennsylvania University of Pennsylvania
The Lazar laboratory is studying the transcriptional regulation of metabolism. We are particularly focused on the role played by nuclear receptors. The Penn Diabetes Research Center participates in the nationwide inter-disciplinary program established over forty years ago by the NIDDK to foster research and training in the areas of diabetes and related endocrine and metabolic disorders.

Diabetes Centers Overview

Diabetes Centers

NIDDK Diabetes Centers

The NIDDK-supported Diabetes Research Centers (DRCs) are part of an integrated program of diabetes and related endocrinology and metabolism research. NIDDK’s Diabetes Centers program supports extramural research institutions that have established an existing base of high-quality, diabetes-related research. Centers provide increased, cost effective collaboration among multidisciplinary groups of investigators at institutions with an established, comprehensive research base in diabetes and related areas of endocrinology and metabolism. DRCs are intended to improve the quality and multidisciplinary nature of research on diabetes by providing shared access to specialized technical resources and expertise. DRCs are intended to facilitate progress in research with the goal of developing new methods to treat, prevent and ultimately cure diabetes mellitus and its complications.

In the Spotlight

Pilot & Feasibility Study
Center Publication
University of Washington Washington 
Neprilysin Is Required for Angiotensin-(1-7)'s Ability to Enhance Insulin Secretion via Its Proteolytic Activity to Generate Angiotensin-(1-2)., Brar, Gurkirat S., Barrow Breanne M., Watson Matthew, Griesbach Ryan, Choung Edwina, Welch Andrew, Ruzsicska Bela, Raleigh Daniel P., and Zraika Sakeneh , Diabetes, 2017 08, Volume 66, Issue 8, p.2201-2212, (2017)
NIDDK Center
The Cystic Fibrosis Research and Translation Centers are part of an integrated program of research support designed to enhance multidisciplinary research in pathogenesis and treatment of cystic fibrosis.
Diabetes Resource
The NKDEP Laboratory Working Group has launched the Creatinine Standardization Program to address inter-laboratory variation in creatinine assay calibration and provide more accurate estimates of GFR.