Diabetes Research Centers (P30 Clinical Trial Optional)
This Funding Opportunity Announcement (FOA) invites applications for Diabetes Research Centers that are designed to support and enhance the national research effort in diabetes, its complications, and related endocrine and metabolic diseases. Diabetes Research Centers support two primary research-related activities: Research Core services and a Pilot and Feasibility (P and F) program.

DIABETES RESEARCH CENTERS

Richard E Ostlund Jr MD Washington University in St Louis Washington University in St Louis
Dr. Richard Ostlund is a professor of Medicine in the Division of Endocrinology, Metabolism and Lipid Research at Washington University School of Medicine in St. Louis. Dr. Ostlund is an acknowledged leader in the field of human cholesterol measurement specializing in general endocrinology, lipid metabolism, diabetes, thyroid disease and nutrition. TThe mission of the Washington University School of Medicine (WUSM) Diabetes Research Center (DRC) is to support and enhance research in diabetes and related metabolic diseases.
Mary-Elizabeth Patti MD Joslin Diabetes Center Joslin Diabetes Center
The laboratory of Mary-Elizabeth Patti, MD focuses on mechanisms by which environmental or nutritional risk factors (e.g. obesity, prenatal and early postnatal nutrition) influence gene expression and metabolic function in tissues critical for insulin sensitivity and glucose tolerance. Since its inception in 1898, the primary mission of the Joslin Diabetes Center has been to care for people with diabetes, and conduct research to provide new knowledge about diabetes and its complications that will lead to new treatments, prevention and/or cure of these disorders.
Martin G Myers Jr MD PhD University of Michigan University of Michigan
Dr. Myers’ research focuses on the processes that enable the body to respond normally to insulin, and how problems in these pathways contribute to the development of insulin resistance and diabetes. The goal of the Michigan Diabetes Research Center (MDRC) is to establish, promote, and enhance multidisciplinary and collaborative basic biomedical and clinical research among member investigators studying diabetes, its complications, and related endocrine and metabolic disorders.
Laurie J Goodyear Laurie J Goodyear PhD MS Joslin Diabetes Center Joslin Diabetes Center
Work in the Goodyear lab has uncovered many of the basic mechanisms that underlie the effects of exercise on metabolism, and has successfully translated many of these findings into humans. Since its inception in 1898, the primary mission of the Joslin Diabetes Center has been to care for people with diabetes, and conduct research to provide new knowledge about diabetes and its complications that will lead to new treatments, prevention and/or cure of these disorders.
Pamela L Mellon PhD UCSD-UCLA UCSD-UCLA
We are interested in how the brain controls reproduction through the neuroendocrine system with emphases on development, hormone signaling, gene expression, circadian rhythm, and mouse models of human disease. The overall mission of the UCSD-UCLA DRC is to foster research in theprevention and treatment of diabetes and its complications, and to improve the lives of patients suffering from this devastating disease.
Klaus Kaestner PhD University of Pennsylvania University of Pennsylvania
Dr. Kaestner’s lab is employing modern genetic, genomic and epigenomic approaches to understand the molecular mechanisms of organogenesis and physiology of the liver, pancreas and gastrointestinal tract. The Penn Diabetes Research Center participates in the nationwide inter-disciplinary program established over forty years ago by the NIDDK to foster research and training in the areas of diabetes and related endocrine and metabolic disorders.
James F Markmann MD PhD Boston Area Boston Area
James F. Markmann MD, PhD is the Chief of the Division of Transplant Surgery and Director of Clinical Operations at the Transplant Center at Massachusetts General Hospital, and the Claude Welch Professor of Surgery at Harvard Medical School. The Boston Area Diabetes Endocrinology Research Center is a consortium of laboratory-based and clinical investigators whose efforts are directed toward addressing many of the major research questions bearing on the etiology, pathogenesis, treatment and cure of type 1 and type 2 diabetes.
Amy Wagers Amy Wagers PhD Joslin Diabetes Center Joslin Diabetes Center
Work in Amy Wagers' laboratory focuses on defining how changes in stem cell activity impact tissue regeneration throughout life and identifying the physiological and pathological signals that modulate stem cell function in an age-dependent manner. Since its inception in 1898, the primary mission of the Joslin Diabetes Center has been to care for people with diabetes, and conduct research to provide new knowledge about diabetes and its complications that will lead to new treatments, prevention and/or cure of these disorders.
Fumihiko Urano Fumihiko Urano MD PhD Washington University in St Louis Washington University in St Louis
Dr. Urano’s current main focus is to find a cure for juvenile diabetes and genetic forms of diabetes including Type 1 diabetes and Wolfram syndrome using stem cell-based therapeutics and gene-based diagnostics. TThe mission of the Washington University School of Medicine (WUSM) Diabetes Research Center (DRC) is to support and enhance research in diabetes and related metabolic diseases.
Andrew Wolfe Andrew Wolfe PhD Johns Hopkins University - University of Maryland Johns Hopkins University - University of Maryland
The Andrew Wolfe Laboratory researches the development and functional regulation of the hypothalamic-pituitary-gonadal axis which controls reproduction. The Johns Hopkins University - University of Maryland Diabetes Research Center fosters collaborative, multidisciplinary diabetes and endocrinology research, and translates that research into programs that advance the diagnosis and management of diabetes mellitus by health care professionals.
Alvin C Powers MD Vanderbilt University Vanderbilt University
The purpose of our research is to understand how glucose stimulates insulin secretion by pancreatic islet cells and to characterize and reverse abnormalities in this process that are present in diabetes. The Vanderbilt Diabetes Research and Training Center (DRTC), is a NIH-sponsored Diabetes Center that facilitates the discovery, application, and translation of scientific knowledge to improve the lives of people with diabetes.
Carmella Evans-Molina Carmella Evans-Molina MD PhD Indiana University Indiana University
The goals of Dr. Evans-Molina’s research program are (1) to define the molecular and inflammatory etiologies of b cell dysfunction in Type 1 and Type 2 diabetes and (2) to identify novel stem cell based strategies to improve b cell survival in diabetes. The Center for Diabetes and Metabolic Diseases (CDMD) at IU School of Medicine is a world-renowned center focused on centralizing and fostering research along five fundamental themes to strengthen the diabetes research base throughout Indiana.
W Timothy Garvey W Timothy Garvey MD University of Alabama at Birmingham University of Alabama at Birmingham
The Garvey laboratory is interested in the molecular, metabolic, and genetic basis of type 2 diabetes mellitus, insulin resistance, and obesity. The Diabetes Research and Training Center (DRC) focuses on developing new methods to treat, prevent, and ultimately cure diabetes and its complications.
Joseph A Baur Joseph A Baur PhD University of Pennsylvania University of Pennsylvania
The Baur lab is interested in the basic mechanisms that lead to aging. Age is the most important risk factor for many of the diseases affecting Western society today, including cancer, cardiovascular disease, and neurodegenerative disorders. The Penn Diabetes Research Center participates in the nationwide inter-disciplinary program established over forty years ago by the NIDDK to foster research and training in the areas of diabetes and related endocrine and metabolic disorders.
Edward Horton Edward Horton MD Joslin Diabetes Center Joslin Diabetes Center
Dr. Horton major interests include obesity and insulin resistance as they relate to diabetes mellitus and cardiovascular disease. Since its inception in 1898, the primary mission of the Joslin Diabetes Center has been to care for people with diabetes, and conduct research to provide new knowledge about diabetes and its complications that will lead to new treatments, prevention and/or cure of these disorders.
Rebecca Hull-Meichle Rebecca Hull-Meichle PhD University of Washington University of Washington
My research focuses on cellular mechanisms underlying islet secretory dysfunction and loss of beta-cell mass in diabetes. The University of Washington (UW) Diabetes Research Center (DRC) at the University of Washington is one of 16 Diabetes Research Centers sponsored by the National Institutes of Health to promote basic, translational, and clinical research on diabetes and related metabolic disorders.

Diabetes Centers Overview

Diabetes Centers

NIDDK Diabetes Centers

The NIDDK-supported Diabetes Research Centers (DRCs) are part of an integrated program of diabetes and related endocrinology and metabolism research. NIDDK’s Diabetes Centers program supports extramural research institutions that have established an existing base of high-quality, diabetes-related research. Centers provide increased, cost effective collaboration among multidisciplinary groups of investigators at institutions with an established, comprehensive research base in diabetes and related areas of endocrinology and metabolism. DRCs are intended to improve the quality and multidisciplinary nature of research on diabetes by providing shared access to specialized technical resources and expertise. DRCs are intended to facilitate progress in research with the goal of developing new methods to treat, prevent and ultimately cure diabetes mellitus and its complications.

In the Spotlight

Pilot & Feasibility Study
Center Publication
Boston Area Boston Area 
Selective Chemical Inhibition of PGC-1α Gluconeogenic Activity Ameliorates Type 2 Diabetes., Sharabi, Kfir, Lin Hua, Tavares Clint D. J., Dominy John E., Camporez Joao Paulo, Perry Rachel J., Schilling Roger, Rines Amy K., Lee Jaemin, Hickey Marc, et al. , Cell, 2017 03 23, Volume 169, Issue 1, p.148-160.e15, (2017)
NIDDK Center
The Nutrition Obesity Centers integrate, coordinate, and foster interdisciplinary basic, clinical, and public health research by established investigators actively conducting programs of high-quality research related to common nutritional sciences and/or obesity theme or themes.
Diabetes Resource
The primary goal of A2ALL is to provide valuable information on the outcomes of both potential and actual recipients and their donors who have been evaluated for adult-to-adult living donor liver transplantation.