Diabetes Research Centers (P30 Clinical Trial Optional)
This Funding Opportunity Announcement (FOA) invites applications for Diabetes Research Centers that are designed to support and enhance the national research effort in diabetes, its complications, and related endocrine and metabolic diseases. Diabetes Research Centers support two primary research-related activities: Research Core services and a Pilot and Feasibility (P and F) program.

DIABETES RESEARCH CENTERS

Sakeneh Zraika Sakeneh Zraika PhD University of Washington University of Washington
Dr. Sakeneh Zraika received in her PhD from the University of Melbourne, Australia and her Postgraduate Fellowship from the University of Washington. The University of Washington (UW) Diabetes Research Center (DRC) at the University of Washington is one of 16 Diabetes Research Centers sponsored by the National Institutes of Health to promote basic, translational, and clinical research on diabetes and related metabolic disorders.
Edward Horton Edward Horton MD Joslin Diabetes Center Joslin Diabetes Center
Dr. Horton major interests include obesity and insulin resistance as they relate to diabetes mellitus and cardiovascular disease. Since its inception in 1898, the primary mission of the Joslin Diabetes Center has been to care for people with diabetes, and conduct research to provide new knowledge about diabetes and its complications that will lead to new treatments, prevention and/or cure of these disorders.
Pamela L Mellon PhD UCSD-UCLA UCSD-UCLA
We are interested in how the brain controls reproduction through the neuroendocrine system with emphases on development, hormone signaling, gene expression, circadian rhythm, and mouse models of human disease. The overall mission of the UCSD-UCLA DRC is to foster research in theprevention and treatment of diabetes and its complications, and to improve the lives of patients suffering from this devastating disease.
Stephen A Liebhaber MD University of Pennsylvania University of Pennsylvania
Dr. Liebhaber's research interests are the roles of chromatin structure and epigenetic controls in eucaryotic gene activation and mRNA-protein interactions in control of eucarytic mRNA stability and expression. The Penn Diabetes Research Center participates in the nationwide inter-disciplinary program established over forty years ago by the NIDDK to foster research and training in the areas of diabetes and related endocrine and metabolic disorders.
Fumihiko Urano Fumihiko Urano MD PhD Washington University in St Louis Washington University in St Louis
Dr. Urano’s current main focus is to find a cure for juvenile diabetes and genetic forms of diabetes including Type 1 diabetes and Wolfram syndrome using stem cell-based therapeutics and gene-based diagnostics. TThe mission of the Washington University School of Medicine (WUSM) Diabetes Research Center (DRC) is to support and enhance research in diabetes and related metabolic diseases.
Mark O Goodarzi MD PhD UCSD-UCLA UCSD-UCLA

The laboratory of Mark O. Goodarzi, MD, PhD, seeks to identify genetic factors underlying conditions related to insulin resistance and the metabolic syndrome, using a population genetic approach.

The overall mission of the UCSD-UCLA DRC is to foster research in theprevention and treatment of diabetes and its complications, and to improve the lives of patients suffering from this devastating disease.
Kevin D Niswender MD PhD Vanderbilt University Vanderbilt University
The Niswender lab is interested in the neuroendocrine regulation of feeding and pathogenesis of obesity and makes extensive use of the full translational spectrum of model systems ranging from cell culture and animal models to human investigation. The Vanderbilt Diabetes Research and Training Center (DRTC), is a NIH-sponsored Diabetes Center that facilitates the discovery, application, and translation of scientific knowledge to improve the lives of people with diabetes.
Dennis Brown Dennis Brown PhD Boston Area Boston Area
Dennis Brown is a Ph. D. cell biologist who specializes in the use of state-of-the art fluorescence imaging and electron microscopy techniques to follow and dissect physiologically-relevant membrane protein trafficking events in epithelial and non-epithelial cells. The Boston Area Diabetes Endocrinology Research Center is a consortium of laboratory-based and clinical investigators whose efforts are directed toward addressing many of the major research questions bearing on the etiology, pathogenesis, treatment and cure of type 1 and type 2 diabetes.
W Timothy Garvey W Timothy Garvey MD University of Alabama at Birmingham University of Alabama at Birmingham
The Garvey laboratory is interested in the molecular, metabolic, and genetic basis of type 2 diabetes mellitus, insulin resistance, and obesity. The Diabetes Research and Training Center (DRC) focuses on developing new methods to treat, prevent, and ultimately cure diabetes and its complications.
Manami Hara Manami Hara PhD University of Chicago University of Chicago
Dr. Hara's research focuses on the identification and characterization of the cells that define the lineage that gives rise to the pancreatic beta cell. The University of Chicago Diabetes Research and Training Center (DRTC) provides resources for the support and coordination of the research and training activities in diabetes and related metabolic and endocrine disorders of a large and growing number of independently funded but highly interactive investigators.
Joseph A Baur Joseph A Baur PhD University of Pennsylvania University of Pennsylvania
The Baur lab is interested in the basic mechanisms that lead to aging. Age is the most important risk factor for many of the diseases affecting Western society today, including cancer, cardiovascular disease, and neurodegenerative disorders. The Penn Diabetes Research Center participates in the nationwide inter-disciplinary program established over forty years ago by the NIDDK to foster research and training in the areas of diabetes and related endocrine and metabolic disorders.
Julian P Whitelegge Julian P Whitelegge PhD UCSD-UCLA UCSD-UCLA
Julian Whitelegge received his Ph.D. from Imperial College of Science and Technology, University of London in 1989 and became heavily involved in mass spectrometry research in the mid nineties. The overall mission of the UCSD-UCLA DRC is to foster research in theprevention and treatment of diabetes and its complications, and to improve the lives of patients suffering from this devastating disease.
Jill P Crandall Jill P Crandall MD Albert Einstein College of Medicine Albert Einstein College of Medicine
Dr. Crandall is Director of the Diabetes Clinical Trials Unit and co-director of the DRTC Clinical Research Facilitation Core. She is an experienced clinical investigator with a joint appointments in the Divisions of Endocrinology and Geriatrics. The Einstein-Mount Sinai Diabetes Research Center (ES-DRC) comprises a vibrant, extensive, diverse, well-funded and highly productive program that provides the foundation for high-quality and cutting-edge research in diabetes and related studies in obesity, metabolism and endocrinology.
George L King George L King MD Joslin Diabetes Center Joslin Diabetes Center
My laboratory studies the mechanism by which hyperglycemia and insulin resistance are causing diabetic retinopathy, nephropathy and cardiovascular diseases. Since its inception in 1898, the primary mission of the Joslin Diabetes Center has been to care for people with diabetes, and conduct research to provide new knowledge about diabetes and its complications that will lead to new treatments, prevention and/or cure of these disorders.
Domenico Accili Domenico Accili MD Columbia University Columbia University
The Accili laboratory studies the mechanism of insulin action and the pathogenesis of diabetes, with a focus on pancreatic beta cell failure. The Columbia University Diabetes and Endocrinology Research Center provides research support for investigators pursuing research on diabetes and metabolic disorders.
Bradford Lowell MD PhD Boston Area Boston Area
The Lowell Lab utilizes genetic engineering techniques in mice, in conjunction with electrophysiology, optogenetics, pharmacogenetics and rabies mapping, to elucidate central neurocircuits controlling feeding behavior, body weight homeostasis, and fuel metabolism. The Boston Area Diabetes Endocrinology Research Center is a consortium of laboratory-based and clinical investigators whose efforts are directed toward addressing many of the major research questions bearing on the etiology, pathogenesis, treatment and cure of type 1 and type 2 diabetes.

Diabetes Centers Overview

Diabetes Centers

NIDDK Diabetes Centers

The NIDDK-supported Diabetes Research Centers (DRCs) are part of an integrated program of diabetes and related endocrinology and metabolism research. NIDDK’s Diabetes Centers program supports extramural research institutions that have established an existing base of high-quality, diabetes-related research. Centers provide increased, cost effective collaboration among multidisciplinary groups of investigators at institutions with an established, comprehensive research base in diabetes and related areas of endocrinology and metabolism. DRCs are intended to improve the quality and multidisciplinary nature of research on diabetes by providing shared access to specialized technical resources and expertise. DRCs are intended to facilitate progress in research with the goal of developing new methods to treat, prevent and ultimately cure diabetes mellitus and its complications.

In the Spotlight

Pilot & Feasibility Study
Center Publication
University of Washington Washington 
Microglial Inflammatory Signaling Orchestrates the Hypothalamic Immune Response to Dietary Excess and Mediates Obesity Susceptibility., Valdearcos, Martin, Douglass John D., Robblee Megan M., Dorfman Mauricio D., Stifler Daniel R., Bennett Mariko L., Gerritse Irene, Fasnacht Rachael, Barres Ben A., Thaler Joshua P., et al. , Cell Metab, 2017 Jul 05, Volume 26, Issue 1, p.185-197.e3, (2017)
NIDDK Center
The Cystic Fibrosis Research and Translation Centers are part of an integrated program of research support designed to enhance multidisciplinary research in pathogenesis and treatment of cystic fibrosis.
Diabetes Resource
The centers that make up the ACE program conduct clinical trials and basic research on new immune-based therapies for autoimmune diseases.