Diabetes Research Centers (P30 Clinical Trial Optional)
This Funding Opportunity Announcement (FOA) invites applications for Diabetes Research Centers that are designed to support and enhance the national research effort in diabetes, its complications, and related endocrine and metabolic diseases. Diabetes Research Centers support two primary research-related activities: Research Core services and a Pilot and Feasibility (P and F) program.

DIABETES RESEARCH CENTERS

Kieren Mather Kieren Mather MD Indiana University Indiana University
Dr Mather’s research focuses on metabolic dysfunction in diabetes and pre diabetic obesity in humans, and how this metabolic dysfunction influences cardiac and vascular function. The Center for Diabetes and Metabolic Diseases (CDMD) at IU School of Medicine is a world-renowned center focused on centralizing and fostering research along five fundamental themes to strengthen the diabetes research base throughout Indiana.
Raghavendra G Mirmira MD PhD Indiana University Indiana University
Dr. Mirmira’s research program over the past 10 years has centered upon the biology of islets as it relates to islet development/growth, maintenance, and survival. The Center for Diabetes and Metabolic Diseases (CDMD) at IU School of Medicine is a world-renowned center focused on centralizing and fostering research along five fundamental themes to strengthen the diabetes research base throughout Indiana.
Rexford S Ahima Rexford S Ahima MD PhD Johns Hopkins University - University of Maryland Johns Hopkins University - University of Maryland
Dr. Ahima is the Director of the Division of Endocrinology, Diabetes and Metabolism, Bloomberg Distinguished Professor of Diabetes in the Schools of Medicine, Public Health and Nursing, and the leader of the Johns Hopkins Diabetes Initiative. The Johns Hopkins University - University of Maryland Diabetes Research Center fosters collaborative, multidisciplinary diabetes and endocrinology research, and translates that research into programs that advance the diagnosis and management of diabetes mellitus by health care professionals.
Jeffrey H Miner PhD Washington University in St Louis Washington University in St Louis
A major interest of my laboratory is the role of basement membrane components in kidney function and disease, with particular emphasis on the glomerular basement membrane (GBM) as a component of the glomerular filtration barrier to albumin. TThe mission of the Washington University School of Medicine (WUSM) Diabetes Research Center (DRC) is to support and enhance research in diabetes and related metabolic diseases.
Matthew J Tyska Matthew J Tyska MD Vanderbilt University Vanderbilt University
The overarching goal of the Tyska Laboratory is to understand how transporting epithelial cells assemble a functional apical surface. Intestinal epithelial cells in particular build one of the most elaborate apical specializations, an array of microvilli known as the brush border. The Vanderbilt Diabetes Research and Training Center (DRTC), is a NIH-sponsored Diabetes Center that facilitates the discovery, application, and translation of scientific knowledge to improve the lives of people with diabetes.
Michael McManus PhD UCSF UCSF
The McManus lab studies fundamental processes relating to mammalian gene expression. We take high-throughput approaches, analyzing hundreds of thousands to millions of experiments at once, using complex libraries coupled to deep sequencing. The University of California San Francisco Diabetes Research Center (UCSF DRC) is one of only 16 research centers established by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to accelerate basic and clinical research into diabetes.
Ronald Cohen Ronald Cohen MD University of Chicago University of Chicago
Dr. Cohen is a skilled endocrinologist whose research explores the relationship between diabetes and adipocyte — a complex endocrine cell that regulates feeding behavior and insulin sensitivity. Through his research findings, Dr. Cohen is working to develop novel therapies for the treatment of obesity and type 2 diabetes. The University of Chicago Diabetes Research and Training Center (DRTC) provides resources for the support and coordination of the research and training activities in diabetes and related metabolic and endocrine disorders of a large and growing number of independently funded but highly interactive investigators.
Fredric Kraemer MD Stanford University Stanford University
Dr. Fredric Kraemer is the Chief of the Division of Endocrinology, Gerontology and Metabolism. He is a board certified endocrinologist for over 35 years who specializes in the treatment diabetes mellitus, particularly type 1 diabetes, and the treatment of lipid disorders, such as elevated cholesterol or triglycerides. The mission of the Stanford Diabetes Research Center is to support basic and clinical research to discover, apply and translate science about diabetes and it complications, to improve health and wellness.
Ji Lei MD MBA Boston Area Boston Area
Dr. Ji Lei is the director of the special service GMP facility for human islet/cell isolation and transplantation at Massachusetts General Hospital. The Boston Area Diabetes Endocrinology Research Center is a consortium of laboratory-based and clinical investigators whose efforts are directed toward addressing many of the major research questions bearing on the etiology, pathogenesis, treatment and cure of type 1 and type 2 diabetes.
Matthew Krummel Matthew Krummel, PhD UCSF UCSF

Our work focusses on understanding patterns of immune cell-cell interactions and how these generate “the immune system”.

The University of California San Francisco Diabetes Research Center (UCSF DRC) is one of only 16 research centers established by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to accelerate basic and clinical research into diabetes.
Streamson C Chua Jr Streamson C Chua Jr MD PhD Albert Einstein College of Medicine Albert Einstein College of Medicine
Dr. Streamson Chua's group is interested in genetic contribution to the chronic disease of obesity, diabetes, and diabetes complications. The Einstein-Mount Sinai Diabetes Research Center (ES-DRC) comprises a vibrant, extensive, diverse, well-funded and highly productive program that provides the foundation for high-quality and cutting-edge research in diabetes and related studies in obesity, metabolism and endocrinology.
Gerald I Shulman Gerald I Shulman MD PhD Yale University Yale University
Dr. Shulman is the George R. Cowgill Professor of Medicine, Cellular & Molecular Physiology and Physiological Chemistry at Yale University, where he serves as Co-Director of the Yale Diabetes Research Center and Director of the Yale Mouse Metabolic Phenotyping Center. The Yale Diabetes Research Center (DRC) was established in the spring of 1993 with the goal of promoting research in diabetes and related metabolic and endocrine disorders at the university.
Jill P Crandall Jill P Crandall MD Albert Einstein College of Medicine Albert Einstein College of Medicine
Dr. Crandall is Director of the Diabetes Clinical Trials Unit and co-director of the DRTC Clinical Research Facilitation Core. She is an experienced clinical investigator with a joint appointments in the Divisions of Endocrinology and Geriatrics. The Einstein-Mount Sinai Diabetes Research Center (ES-DRC) comprises a vibrant, extensive, diverse, well-funded and highly productive program that provides the foundation for high-quality and cutting-edge research in diabetes and related studies in obesity, metabolism and endocrinology.
David P Olson David P Olson MD PhD University of Michigan University of Michigan
Using novel mouse models, Dr. Olson is exploring gene expression changes in specific neuronal populations in the brain that are known to be important in regulating energy balance; these studies are directed at examining the link between gene expression in specific areas of the brain and altered metabolism. The goal of the Michigan Diabetes Research Center (MDRC) is to establish, promote, and enhance multidisciplinary and collaborative basic biomedical and clinical research among member investigators studying diabetes, its complications, and related endocrine and metabolic disorders.
Darleen Sandoval Darleen Sandoval PhD University of Michigan University of Michigan
Dr. Sandoval's current work utilizes basic research strategies that use a combination of molecular and physiological techniques with the goal of generating better therapeutic options for obesity and type 2 diabetes. The goal of the Michigan Diabetes Research Center (MDRC) is to establish, promote, and enhance multidisciplinary and collaborative basic biomedical and clinical research among member investigators studying diabetes, its complications, and related endocrine and metabolic disorders.
Joseph Avruch Joseph Avruch MD PhD Boston Area Boston Area
Dr. Avruch is a Professor of Medicine at the Harvard Medical School in the Department of Molecular Biology, and has been Chief of the Diabetes Unit in the department of Medicine at the MGH since 1979. The Boston Area Diabetes Endocrinology Research Center is a consortium of laboratory-based and clinical investigators whose efforts are directed toward addressing many of the major research questions bearing on the etiology, pathogenesis, treatment and cure of type 1 and type 2 diabetes.

Diabetes Centers Overview

Diabetes Centers

NIDDK Diabetes Centers

The NIDDK-supported Diabetes Research Centers (DRCs) are part of an integrated program of diabetes and related endocrinology and metabolism research. NIDDK’s Diabetes Centers program supports extramural research institutions that have established an existing base of high-quality, diabetes-related research. Centers provide increased, cost effective collaboration among multidisciplinary groups of investigators at institutions with an established, comprehensive research base in diabetes and related areas of endocrinology and metabolism. DRCs are intended to improve the quality and multidisciplinary nature of research on diabetes by providing shared access to specialized technical resources and expertise. DRCs are intended to facilitate progress in research with the goal of developing new methods to treat, prevent and ultimately cure diabetes mellitus and its complications.

In the Spotlight

Pilot & Feasibility Study
Center Publication
Boston Area Boston Area Albert Einstein College of Medicine Einstein 
Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms., Rusu, Victor, Hoch Eitan, Mercader Josep M., Tenen Danielle E., Gymrek Melissa, Hartigan Christina R., DeRan Michael, von Grotthuss Marcin, Fontanillas Pierre, Spooner Alexandra, et al. , Cell, 2017 Jun 29, Volume 170, Issue 1, p.199-212.e20, (2017)
NIDDK Center
The Nutrition Obesity Centers integrate, coordinate, and foster interdisciplinary basic, clinical, and public health research by established investigators actively conducting programs of high-quality research related to common nutritional sciences and/or obesity theme or themes.
Diabetes Resource
The NKDEP Laboratory Working Group has launched the Creatinine Standardization Program to address inter-laboratory variation in creatinine assay calibration and provide more accurate estimates of GFR.