First Trimester Plasma Glucose Values in Women without Diabetes are Associated with Risk for Congenital Heart Disease in Offspring.
| Citation | . “First Trimester Plasma Glucose Values In Women Without Diabetes Are Associated With Risk For Congenital Heart Disease In Offspring.”. The Journal Of Pediatrics, pp. 275-278. |
| Center | Stanford University |
| Author | Emmi I T Helle, Preston Biegley, Joshua W Knowles, Joseph B Leader, Sarah Pendergrass, Wei Yang, Gerald R Reaven, Gary M Shaw, Marylyn Ritchie, James R Priest |
| Keywords | congenital heart disease, congenital malformation, diabetes, Oral glucose tolerance test, plasma glucose |
| Abstract |
In a retrospective study of 19 171 mother-child dyads, elevated random plasma glucose values during early pregnancy were directly correlated with increased risk for congenital heart disease in offspring. Plasma glucose levels proximal to the period of cardiac development may represent a modifiable risk factor for congenital heart disease in expectant mothers without diabetes. |
| Year of Publication |
2018
|
| Journal |
The Journal of pediatrics
|
| Volume |
195
|
| Number of Pages |
275-278
|
| Date Published |
12/2018
|
| ISSN Number |
1097-6833
|
| DOI |
10.1016/j.jpeds.2017.10.046
|
| Alternate Journal |
J. Pediatr.
|
| PMID |
29254757
|
| PMCID |
PMC5869072
|
| Download citation |