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Cystic Fibrosis Research Development Program

The Cystic Fibrosis Research Development Program (CF RDP) Pilot Projects are awarded through the Dartmouth Cystic Fibrosis Research Center. The goal of the research development program is to leverage diabetes expertise at NIDDK funded DRCs and CDTRs to investigate cystic fibrosis-related diabetes.

The Pilot and Feasibility studies will address important issues in the progression of cystic fibrosis-related diabetes treatment and disease, develop and test novel hypotheses and methodologies, and support promising new investigators as CF researchers.

Pilot Projects and Awardees

FY2024

Giordano, Nicholas PhD RN FAAN, Georgia Center for Diabetes Translation Research
A Multi-omics Approach to Discern the Role of Diabetes on Quality of Life and Symptom Phenotypes Among Individuals Living with Cystic Fibrosis

Gordon, Sharon PhD, University of Washington Diabetes Research Center
Evaluation of insulin resistance affected by CF modulators in skeletal muscle cells

Shah, Viral MD, Indiana University Diabetes Research Center
A novel continuous glucose monitoring based method to define prediabetes in people with cystic fibrosis

FY2023

Hassan S Dashti PhD RD, Boston Area Diabetes Endocrinology Research Center
Investigating the effects of tube feeds on glycemia and sleep in adults with Cystic Fibrosis-Related Diabetes

Kim, Seung MD PhD RD, Stanford Diabetes Research Center Investigating molecular mechanisms underlying cystic fibrosis-related diabetes using snRNS sequencing of FFPE donor tissue

FY2022

Dieter Egli PhD, Columbia University Diabetes Research Center
Cystic Fibrosis Transmembrane Conductance Regulatory Protein (CFTR) function in human beta cells in a stem cell model of Cystic Fibrosis Related Diabetes (CFRD)

Kyle Gaulton PhD, UCSD-UCLA Diabetes Research Center
Single cell analysis of the human pancreas in cystic fibrosis