Weight Change 2 Years After Termination of the Intensive Lifestyle Intervention in the Look AHEAD Study.
| Citation | . “Weight Change 2 Years After Termination Of The Intensive Lifestyle Intervention In The Look Ahead Study.”. Obesity (Silver Spring, Md.), pp. 893-901. |
| Center | University of Washington |
| Author | Look AHEAD Research Group, Ariana M Chao, Thomas A Wadden, Robert I Berkowitz, George Blackburn, Paula Bolin, Jeanne M Clark, Mace Coday, Jeffrey M Curtis, Linda M Delahanty, Gareth R Dutton, Mary Evans, Linda J Ewing, John P Foreyt, Linda J Gay, Edward W Gregg, Helen P Hazuda, James O Hill, Edward S Horton, Denise K Houston, John M Jakicic, Robert W Jeffery, Karen C Johnson, Steven E Kahn, William C Knowler, Anne Kure, Katherine L Michalski, Maria G Montez, Rebecca H Neiberg, Jennifer Patricio, Anne Peters, Xavier Pi-Sunyer, Henry Pownall, David Reboussin, Bruce Redmon, Jack Rejeski, Helmut Steinburg, Martha Walker, Donald A Williamson, Rena R Wing, Holly Wyatt, Susan Z Yanovski, Ping Zhang |
| Abstract |
OBJECTIVE: This study evaluated weight changes after cessation of the 10-year intensive lifestyle intervention (ILI) in the Look AHEAD (Action for Health in Diabetes) study. It was hypothesized that ILI participants would be more likely to gain weight during the 2-year observational period following termination of weight-loss-maintenance counseling than would participants in the diabetes support and education (DSE) control group. METHODS: Look AHEAD was a randomized controlled trial that compared the effects of ILI and DSE on cardiovascular morbidity and mortality in participants with overweight/obesity and type 2 diabetes. Look AHEAD was converted to an observational study in September 2012. RESULTS: Two years after the end of the intervention (EOI), ILI and DSE participants lost a mean (SE) of 1.2 (0.2) kg and 1.8 (0.2) kg, respectively (P = 0.003). In addition, 31% of ILI and 23.9% of DSE participants gained ≥ 2% (P < 0.001) of EOI weight, whereas 36.3% and 45.9% of the respective groups lost ≥ 2% of EOI weight (P = 0.001). Two years after the EOI, ILI participants reported greater use of weight-control behaviors than DSE participants. CONCLUSIONS: Both groups lost weight during the 2-year follow-up period, but more ILI than DSE participants gained ≥ 2% of EOI weight. Further understanding is needed of factors that affected long-term weight change in both groups. |
| Year of Publication |
2020
|
| Journal |
Obesity (Silver Spring, Md.)
|
| Volume |
28
|
| Issue |
5
|
| Number of Pages |
893-901
|
| Date Published |
12/2020
|
| ISSN Number |
1930-739X
|
| DOI |
10.1002/oby.22769
|
| Alternate Journal |
Obesity (Silver Spring)
|
| PMID |
32320144
|
| PMCID |
PMC7437140
|
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