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The Prevalence and Specificity of Depression Diagnosis in a Clinic-Based Population of Adults With Type 2 Diabetes Mellitus.

Citation
Golden, S. H., et al. “The Prevalence And Specificity Of Depression Diagnosis In A Clinic-Based Population Of Adults With Type 2 Diabetes Mellitus.”. Psychosomatics, pp. 28-37.
Author Sherita Hill Golden, Nina Shah, Mohammad Naqibuddin, Jennifer L Payne, Felicia Hill-Briggs, Gary S Wand, Nae-Yuh Wang, Susan Langan, Constantine Lyketsos
Keywords anxiety disorders, Major depressive disorder, minor depression, type 2 diabetes mellitus
Abstract

OBJECTIVE: To estimate the crude prevalence of minor depressive disorder (MinD) in a clinic-based population of adults with type 2 diabetes.

METHODS: We screened a clinical sample of 702 adults with type 2 diabetes for depressive symptoms using the Patient Health Questionnaire-2 and performed a structured diagnostic psychiatric interview on 52 screen-positive and a convenience sample of 51 screen-negative individuals. Depressive disorder diagnoses were made using Diagnostic and Statistical Manual of Mental Disorders IV (DSM-IV) Text Revised criteria and categorized as MinD, major depressive disorder (MDD), or no depressive disorder. We estimated prevalence of MinD and MDD and derived 95% CIs.

RESULTS: The crude prevalence of current, past, and current or past MinD was 4.3% (95% CI: 0.9-9.2%), 9.6% (95% CI: 3.9-15.9%), and 13.9% (95% CI: 7.7-21.2%), respectively. The crude prevalence of current, past, and current or past MDD was slightly higher-5.0% (95% CI: 1.9-9.4%), 12.0% (95% CI: 6.1-19.5%), and 17.0% (95% CI: 10.1-24.8%), respectively. There was a high prevalence of coexisting anxiety disorders in individuals with MinD (42.2%) and MDD (8.1%). Hemoglobin A1c levels were not significantly different in individuals with MinD or MDD compared to those without a depressive disorder.

CONCLUSIONS: MinD is comparably prevalent to MDD in patients with type 2 diabetes; both disorders are associated with concomitant anxiety disorders. MinD is not included in the DSM-5; however, our data support continuing to examine patients with chronic medical conditions for MinD.

Year of Publication
2017
Journal
Psychosomatics
Volume
58
Issue
1
Number of Pages
28-37
Date Published
12/2017
ISSN Number
1545-7206
DOI
10.1016/j.psym.2016.08.003
Alternate Journal
Psychosomatics
PMID
27692654
PMCID
PMC5803755
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