The peroxisomes strike BAK: Regulation of peroxisome integrity by the Bcl-2 family.
| Citation | Chipuk, Jerry Edward, and Mark P A Luna-Vargas. “The Peroxisomes Strike BAK: Regulation of Peroxisome Integrity by the Bcl-2 Family”. 2017. The Journal of Cell Biology, vol. 216, no. 3, 2017, pp. 547–549. |
| Center | Albert Einstein College of Medicine |
| Author | Jerry Edward Chipuk, Mark P A Luna-Vargas |
| Abstract |
Within the mitochondrial pathway of apoptosis, VDAC2 controls both the localization and proapoptotic activity of BAK. In this issue, Hosoi et al. (2017. https://doi.org/10.1083/jcb.201605002) find that loss of VDAC2 diverts BAK into peroxisome membranes, revealing the ability of BAK to control peroxisome membrane integrity and the release of soluble peroxisomal matrix proteins. |
| Year of Publication |
2017
|
| Journal |
The Journal of cell biology
|
| Volume |
216
|
| Issue |
3
|
| Number of Pages |
547-549
|
| Date Published |
12/2017
|
| ISSN Number |
1540-8140
|
| DOI |
10.1083/jcb.201701187
|
| Alternate Journal |
J. Cell Biol.
|
| PMID |
28193702
|
| PMCID |
PMC5350527
|
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