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Freesurfer cortical normative data for adults using Desikan-Killiany-Tourville and ex vivo protocols.

Citation
Potvin, O., et al. “Freesurfer Cortical Normative Data For Adults Using Desikan-Killiany-Tourville And Ex Vivo Protocols.”. Neuroimage, pp. 43-64.
Center Washington University in St Louis
Author Olivier Potvin, Louis Dieumegarde, Simon Duchesne, Alzheimer's Disease Neuroimaging Initiative
Keywords aging, Atrophy, magnetic resonance imaging, morphometry, normality, Segmentation, Sex
Abstract

We recently built normative data for FreeSurfer morphometric estimates of cortical regions using its default atlas parcellation (Desikan-Killiany or DK) according to individual and scanner characteristics. We aimed to produced similar normative values for Desikan-Killianny-Tourville (DKT) and ex vivo-based labeling protocols, as well as examine the differences between these three atlases. Surfaces, thicknesses, and volumes of cortical regions were produced using cross-sectional magnetic resonance scans from the same 2713 healthy individuals aged 18-94 years as used in the reported DK norms. Models predicting regional cortical estimates of each hemisphere were produced using age, sex, estimated intracranial volume (eTIV), scanner manufacturer and magnetic field strength (MFS) as predictors. The DKT and DK models generally included the same predictors and produced similar R. Comparison between DK, DKT, ex vivo atlases normative cortical measures showed that the three protocols generally produced similar normative values.

Year of Publication
2017
Journal
NeuroImage
Volume
156
Number of Pages
43-64
Date Published
12/2017
ISSN Number
1095-9572
DOI
10.1016/j.neuroimage.2017.04.035
Alternate Journal
Neuroimage
PMID
28479474
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