Elevated unmethylated and methylated insulin DNA are unique markers of A+β+ ketosis prone diabetes.
| Citation | . “Elevated Unmethylated And Methylated Insulin Dna Are Unique Markers Of A+Β+ Ketosis Prone Diabetes.”. Journal Of Diabetes And Its Complications, pp. 193-195. |
| Center | Indiana University |
| Author | Surya N Mulukutla, Sarah A Tersey, Christiane S Hampe, Raghavendra G Mirmira, Ashok Balasubramanyam |
| Keywords | beta cell death, diabetic ketoacidosis, Insulin DNA, Islet dysfunction, Ketosis prone diabetes |
| Abstract |
A+β+ ketosis prone diabetes (KPD) is associated with slowly progressive autoimmune beta cell destruction. Plasma unmethylated and methylated insulin DNA (biomarkers of ongoing beta cell damage and systemic inflammation, respectively) were elevated in A+β+ KPD compared to all other KPD subgroups. |
| Year of Publication |
2018
|
| Journal |
Journal of diabetes and its complications
|
| Volume |
32
|
| Issue |
2
|
| Number of Pages |
193-195
|
| Date Published |
12/2018
|
| ISSN Number |
1873-460X
|
| DOI |
10.1016/j.jdiacomp.2017.10.013
|
| Alternate Journal |
J. Diabetes Complicat.
|
| PMID |
29175121
|
| PMCID |
PMC6170161
|
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