Management of Hypertension and High Low-Density Lipoprotein in Pediatric Type 1 Diabetes.
| Citation | Katz, Michelle L, et al. “Management of Hypertension and High Low-Density Lipoprotein in Pediatric Type 1 Diabetes”. 2018. The Journal of Pediatrics, vol. 197, 2018, pp. 140–146.e12.  | 
       
| Center | Joslin Diabetes Center | 
| Author | Michelle L Katz, Zijing Guo, Lori M Laffel | 
| Keywords | anti-hypertensive, cholesterol, lipid-lowering | 
| Abstract | 
   OBJECTIVE: To evaluate hypertension and hyperlipidemia management patterns in youth with type 1 diabetes and to assess perceived effectiveness of management strategies and barriers to management. STUDY DESIGN: An electronic survey, including clinical scenarios, fielded to pediatric providers (members of the American Diabetes Association Diabetes in Youth Interest Group, Pediatric Endocrine Society, or T1D Exchange). RESULTS: Respondents (N = 207, 86% MDs, 68% female) were practicing clinicians for youth with type 1 diabetes. As an initial recommendation, the overwhelming majority of respondents (83%-99%) endorsed lifestyle and nonmedical recommendations (eg, improve glycemic control) for hypertension and hyperlipidemia. Yet, few (6%-17%) reported these recommendations as effective. Many respondents (57%) reported referring to another specialist for hypertension, whereas few (8%) reported referring to another specialist for hyperlipidemia management. Approximately one-fifth (21%) of respondents never initiate antihypertensive medications, whereas only 8% never initiate lipid-lowering medication. Among prescribers, the majority of respondents only started antihypertensive or lipid-lowering medications after persistent elevations and in the setting of either ineffective lifestyle or nonmedical interventions or additional cardiovascular risk factors. More than two-thirds of respondents endorsed medications as often effective for hypertension and hyperlipidemia (68% and 69%, respectively). CONCLUSIONS: Pediatric diabetes providers commonly defer prescribing antihypertensive and lipid-lowering medications until nonmedication interventions have been ineffective. Most providers describe medications, but not lifestyle interventions, as often effective. Efforts to align clinical practice with clinical guidelines are needed.  | 
        
| Year of Publication | 
   2018 
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| Journal | 
   The Journal of pediatrics 
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| Volume | 
   197 
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| Number of Pages | 
   140-146.e12 
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| Date Published | 
   12/2018 
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| ISSN Number | 
   1097-6833 
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| DOI | 
   10.1016/j.jpeds.2017.11.059 
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| Alternate Journal | 
   J. Pediatr. 
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| PMCID | 
   PMC6013061 
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| PMID | 
   29395184 
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