Complement C3 and Autophagy Keep the β Cell Alive.
| Citation | . “Complement C3 And Autophagy Keep The Β Cell Alive.”. Cell Metabolism, pp. 4-6. |
| Center | Albert Einstein College of Medicine |
| Author | Miriam Toledo, Rajat Singh |
| Abstract |
Autophagy prevents pancreatic β cell death during obesity, although the mechanism of autophagy activation in the β cell has remained elusive. In this issue of Cell Metabolism, King et al. (2018) show that intracellular complement component C3 interacts with autophagy protein ATG16L1 and protects against β cell death by stimulating autophagy. |
| Year of Publication |
2019
|
| Journal |
Cell metabolism
|
| Volume |
29
|
| Issue |
1
|
| Number of Pages |
4-6
|
| Date Published |
12/2019
|
| ISSN Number |
1932-7420
|
| DOI |
10.1016/j.cmet.2018.12.010
|
| Alternate Journal |
Cell Metab.
|
| PMID |
30625308
|
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