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DERC - Columbia University
1150 Nicholas Ave.
New York, NY NY 10032
[WEBSITE]

The Columbia University Diabetes and Endocrinology Research Center was established in 2003 with the goal of providing research support for investigators pursuing research on diabetes and metabolic disorders. The DERC provides a central support structure to foster collaboration among investigators working in the areas of diabetes, immunology, transplantation, obesity and arteriosclerosis/lipid research and supports their activities by providing shared core resources, funding for pilot/feasibility studies and a common intellectual environment. The Biomedical Research Base of the Columbia DERC is comprised of 72 NIH-, ADA- and JDRF-funded investigators. The DERC supports five shared core facilities: Genomics, Hormone & Metabolite, Protein Expression and Purification, Islet Biology, and Mouse Phenotyping. An administrative Core provides overall logistical support, financial oversight and integration of research efforts and shared core facilities. It also oversees the administration of the P/F program. Additionally, the DERC provides established scientists in other research areas at Columbia University with the opportunity and support to enter the diabetes field, and makes available initial funding for young investigators through a pilot/feasibility grant program.

Cores

Protein : The protein core facility will aid DERC researchers in all aspects of protein production and characterization. Services include production of recombinant proteins in both bacterial and mammalian expression systems; protein purification; protein..

Administration : The administrative core is responsible for the coordination of DERC activities. The Administrative Core oversees program objectives and core utilization, provides logistical..

Molecular Biology, Genomics & Genetics : The function of the Genomics Core is to provide access to skilled service and training in a suite of rapidly changing and expanding biological and computational technologies that enable the acquisition, manipulation, and interpretation of large..

Assay & Analytical : The purpose of the Hormone/Metabolite Core Laboratory is to make available to DERC investigators a variety of analytical techniques that are of interest in the study of diabetes, atherosclerosis, obesity, insulin resistance and related problems...

Animal Physiology & Phenotyping : The Mouse Phenotyping Core is organized around the four services – Histopathology, Body Composition, Multiplex Protein Assays, and Whole Body Metabolic Assessment.The

Islet Cell Biology : The Cell Bank/Immunology Core will provide services and reagents to support the work of DERC investigators in several different research areas. The Core will provide both rodent and human islets to investigators who use them for experimental..

People

Lori Sussel, Ph.D. : Director, Histopathology Core, . Phone: 212-851-5115

Rudolph L. Leibel : Associate Center Director, Director, Genomics Core and Director of P&F and Enrichment Programs, . Phone: 212-851-5257

Yiying Zhang, Ph.D. : Assistant Director, Genomics Core, . Phone: 212-851-5301

Lawrence Shapiro, Ph.D. : Director, Protein Production Core, Columbia University, Dept. of Biochemistry and Molecular Biophysics, 630 West 168th Street, New York, NY 10032, USA. Phone: 212-342-6029

Mary Anne Gawinowicz, Ph.D. : Manager, Protein Production Core, . Phone: 212-305-3631

F. Xavier Pi-Sunyer, M.D., M.P.H. : Director, Hormone and Metabolite Core, . Phone: 212-523-4161

Jeanine Albu, M.D. : Assistant Director, Hormone and Metabolite Core, Obesity Research Center, 1111 Amsterdam Ave. NY 10025. Phone: 212-523-4183

Anthony W. Ferrante, Jr., MD, PhD : Director, Mouse Phenotyping Core, Russ Berrie Pavilion, Room 238, 1150 St.Nicholas Avenue, New York, NY 10032. Phone: 212-851-5322

Domenico Accili, M.D. : Center Director and Director, Islet & Immunology Core, Russ Berrie Pavilion, Room 238, 1150 St.Nicholas Avenue, New York, NY 10032. Phone: 212-851-5332